Lafayette, IN, October 20, 2026 —

Actress Christina Applegate said on her podcast MeSsy that she had been misdiagnosed with Multiple Sclerosis, or MS. She has since been told that she does not have the condition, but continues to experience significant pain and mobility issues, according to the information provided about her remarks.

The diagnosis had also connected Applegate with the MS community, which she had joined. The change in what she has been told about her health has left her uncertain about her condition and about her place in that community.

The available information does not specify when Applegate received the original diagnosis or who later told her she does not have MS. It also does not identify the source or provide details of any medical evaluation. No further explanation of her pain or mobility issues was provided.

Applegate’s account describes a gap between being told she does not have MS and continuing to live with significant symptoms. The information provided does not clarify what is causing those symptoms, what steps may follow, or whether she has received another diagnosis. It therefore offers no basis for drawing conclusions about her health beyond the details she shared.

Her remarks also reflect the personal uncertainty she described after joining a community associated with the diagnosis. The information provided does not include further details about her involvement with that community or how she intends to navigate that connection. Applegate’s comments were made on MeSsy; no episode date or additional verbatim statements were supplied.


Story summarized from the original created by Dorothy Sedovic on www.wlfi.com, see more information here.

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